Characterization of multiple cytomegalovirus drug resistance mutations detected in a hematopoietic stem cell transplant recipient by recombinant phenotyping.
نویسندگان
چکیده
Cytomegalovirus resistance to antivirals is a major problem in transplant recipients. We evaluated the impact of five mutations (A594V, L595F, and E655K in the UL97 gene and V526L and E756K in the UL54 gene), detected in a blood sample from a stem cell transplant recipient, on drug susceptibilities and replicative capacities of recombinant viruses.
منابع مشابه
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ورودعنوان ژورنال:
- Journal of clinical microbiology
دوره 52 11 شماره
صفحات -
تاریخ انتشار 2014